PBT2
Two people are losing language in two different ways. Jan, the filmmaker’s mother, knows exactly what she wants to say, but when stress rises the words won’t come. Len, his uncle, can still talk with effortless charm and wit, yet his past is slipping away from him. He tells stories with total conviction about a life he can no longer remember.
Between them stands PBT2, an experimental drug designed to target the metal-protein chemistry thought to drive neurodegeneration. It is also the life’s work of world-renowned brain pathologist Professor Colin Masters, who has spent decades studying the brain’s slow unravelling.
PBT2 combines poetry, animation, live action and intimate family moments. It moves between the laboratory and the living room, between the molecule and the memory. It asks what a mind is made of, and what remains of a person when words or memories begin to fade.